Supraparticles are large clusters of much smaller colloidal particles. Controlling the shape and anisotropy of supraparticles can enhance their functionality, enabling applications in fields such as optics, magnetics, and medicine. The evaporation of self-lubricating colloidal ouzo droplets is an easy and efficient strategy to create supraparticles, overcoming the problem of the "coffee-stain effect" during drop evaporation. Yet, the parameters that control the shape of the supraparticles formed in such evaporating droplets are not fully understood. Here, we show that the size of the colloidal particles determines the shape of the supraparticle. We compared the shape of the supraparticles made of seven different sizes of spherical silica particles, namely from 20 to 1000 nm, and of the mixtures of small and large colloidal particles at different mixing ratios. Specifically, our in situ measurements revealed that the supraparticle formation proceeds via the formation of a flexible shell of colloidal particles at the rapidly moving interfaces of the evaporating droplet. The time tc0 when the shell ceases to shrink and loses its flexibility is closely related to the size of particles. A lower tc0, as observed for smaller colloidal particles, leads to a flat pancake-like supraparticle, in contrast to a more curved American football-like supraparticle from larger colloidal particles. Furthermore, using a mixture of large and small colloidal particles, we obtained supraparticles that display a spatial variation in particle distribution, with small colloids forming the outer surface of the supraparticle. Our findings provide a guideline for controlling the supraparticle shape and the spatial distribution of the colloidal particles in supraparticles by simply self-lubricating ternary drops filled with colloidal particles.It is fascinating yet challenging to assemble anisotropic nanowires into ordered architectures of high complexity and intriguing functions. We exploited a facile strategy involving oriented etching of a metal-organic fragment (MOF) to advance the rational design of highly ordered nanostructures. As a proof of concept, a microscale MIL-68(In) single crystal was etched with a K3[Co(CN)6] solution to give a microtube composed of aligned MIL-68(In) nanorods. Annealing such a MIL-68(In) microtube readily created an unprecedented branched In2O3 mesocrystal by assembly of In2O3 nanorods aligned in order. The derived ordered-In2O3-ZnIn2S4 is more efficient in catalyzing visible-light-driven H2 evolution (8753 μmol h-1 g-1) outperforming the disordered-In2O3-ZnIn2S4 counterpart (2700 μmol h-1 g-1) as well as many other state-of-the-art ZnIn2S4-based photocatalysts. The ordered architecture significantly boosts the short-range electron transfer in an In2O3-ZnIn2S4 heterojunction but has a negligible impact on the long-range electron transfer among In2O3 mesocrystals. The density functional theory (DFT) calculation reveals that the oriented etching is achieved by the selective binding of the [Co(CN)6]3- etchant on the (110) plane of MIL-68(In), which can drag the In atoms out of the framework in order. Our findings could broaden the technical sense toward advanced photocatalyst design and impose scientific impacts on unveiling how ordered photosystems operate.Long-term specific tracing of the fibroblast activation protein (FAP) has been of great importance because it is heavily expressed by stromal fibroblasts of multiple diseases, and several disorders associated with FAP are chronical. Bioluminescence (BL) imaging has its advantages to detect FAP in vivo since no external excitation is required, but the current FAP-responsive BL probe was constructed by covalently masking the firefly luciferase substrate and easily secreted out from the animal, resulting in transient BL imaging of FAP. To circumvent this problem, a peptide-linked amphiphilic block copolymer-based probe (PABC) was developed and applied to the long-lasting BL image of FAP in vivo. For this purpose, an amphiphilic block copolymer containing an FAP-responsive peptide was fabricated to self-assemble into micelles, which act as a depot to load amounts of d-luciferin for constructing the BL probe. Upon reaction with FAP, the micelle would be destroyed to release the internal d-luciferin for BL emission by a luciferase-catalyzed reaction. By virtue of the high loading capability of micelles, the FAP was determined from 0.5 to 10 ng/mL with a detection limit of 0.105 ng/mL, and the high sensitivity makes the PABC capable of distinguishing cancer cells from normal ones. https://www.selleckchem.com/products/Rapamycin.html Importantly, compared with free d-luciferin, PABC can be used to persistently image the FAP in living cells and in vivo. This characteristic of long-lasting specific tracing of the FAP makes us envision that this BL probe could be used for screening of FAP inhibitors and diagnosing various FAP-related diseases in future.Acid-catalyzed intramolecular reactions of isoindolinone-derived hydroxylactam derivatives bearing enones or enals that afford spiro isoindolinone derivatives and related molecules have been developed. From the hydroxylactam moieties, N-acylenamides were generated in situ and reacted with the enone and the enal moieties via formal [4 + 2] cycloaddition reactions to construct cyclohexanone- and dihydropyran-fused ring systems and the spiro ring systems.Flexible pressure sensors have attracted intense attention because of their widespread applications in electronic skin, human-machine interfaces, and healthcare monitoring. Conductive porous structures are always utilized as active layers to improve the sensor sensitivities. However, flexible pressure sensors derived from traditional foaming techniques have limited structure designability. Besides, random pore distribution causes difference in structure and signal repeatability between different samples even in one batch, therefore limiting the batch production capabilities. Herein, we introduce a structure designable lattice structure pressure sensor (LPS) produced by bottom-up digital light processing (DLP) 3D printing technique, which is capable of efficiently producing 55 high fidelity lattice structure models in 30 min. The LPS shows high sensitivity (1.02 kPa-1) with superior linearity over a wide pressure range (0.7 Pa to 160 kPa). By adjusting the design parameters such as lattice type and layer thickness, the electrical sensitivities and mechanical properties of LPS can be accurately controlled.